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It is currently being studied as a combination therapy with GLP-1 receptor agonists , such as semaglutide and retatrutide, showing synergistic effects in weight management trials

It should also be noted that the weight loss effect of GLP-1 RM can be a drawback in patients who have undergone MBS, especially those who have lost weight successfully post operatively and may be low BMI

and, under accelerated approval, for noncirrhotic MASH with moderate to advanced liver fibrosis in adults

Bellwether Trial Selection and Settlement Prospects Bellwether trials (representative test cases selected to gauge how juries respond to evidence and testimony) will likely begin in early to mid-2026, providing the first courtroom verdicts in this massive litigation